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Antivirals for Respiratory Viral Infections: Problems and Prospects.

Identifieur interne : 001078 ( Main/Exploration ); précédent : 001077; suivant : 001079

Antivirals for Respiratory Viral Infections: Problems and Prospects.

Auteurs : Qiang Liu [République populaire de Chine] ; Yuan-Hong Zhou [République populaire de Chine] ; Feng Ye [République populaire de Chine] ; Zhan-Qiu Yang [République populaire de Chine]

Source :

RBID : pubmed:27486742

Descripteurs français

English descriptors

Abstract

In the past two decades, several newly emerging and reemerging viral respiratory pathogens including several influenza viruses (avian influenza and pandemic influenza), severe acute respiratory syndrome coronavirus (SARS-CoV), and Middle East respiratory syndrome coronavirus (MERS-CoV), have continued to challenge medical and public health systems. Thereafter, the development of cost-effective, broad-spectrum antiviral agents is the urgent mission of both virologists and pharmacologists. Current antiviral developments have focused targets on viral entry, replication, release, and intercellular pathways essential for viral life cycle. Here, we review the current literature on challenges and prospects in the development of these antivirals.

DOI: 10.1055/s-0036-1584803
PubMed: 27486742


Affiliations:


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